Ethyl 2-(3-bromo-4-hydroxyphenyl)acetate → {2'-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-6-hydroxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester

HRID 1216833Notes

Reaction equation

HRID 1216833 reaction equation
[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[O:22][C:23]([N:24]([CH2:25][c:26]1[c:27]([B:36]2[O:37][C:38]([CH3:39])([CH3:40])[C:41]([CH3:42])([CH3:43])[O:44]2)[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]1)[CH2:45][CH3:46])=[O:47].[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([Br:13])[c:9]([OH:12])[cH:10][cH:11]1)=[O:14]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8](-[c:27]2[c:26]([CH2:25][N:24]([C:23]([O:22][CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)=[O:47])[CH2:45][CH3:46])[cH:31][c:30]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:28]2)[c:9]([OH:12])[cH:10][cH:11]1)=[O:14]

Participants

3

Reactant 2

HCID 18620106Ethyl 2-(3-bromo-4-hydroxyphenyl)acetateHCID 66603618(Ethyl)[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethylbenzyl]carbamic acid benzyl ester

Product 1

HCID 66604011{2'-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-6-hydroxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester

Sources & evidence

ORD record
ord-d7ad03a4d1e64594bae5d7d1aee840a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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