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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1217135Generated: November 3, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-difluoro-4-(2-hydroxypropan-2-yl)phenyl]-2-[[6-[(2-hydroxycyclopentyl)oxymethyl]-2-pyridinyl]amino]thiophene-3-carboxamide

https://huagongshe.com/reaction/1217135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant2-[(6-Bromo-2-pyridinyl)methoxy]cyclopentan-1-olHCID 72315999—
Product5-[2,6-difluoro-4-(2-hydroxypropan-2-yl)phenyl]-2-[[6-[(2-hydroxycyclopentyl)oxymethyl]-2-pyridinyl]amino]thiophene-3-carboxamideHCID 178458579—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-0a932ffa7c1e4dd8a13b7983e6ee1915
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)