3-(2,5-Dichloropyrimidin-4-yl)-1H-indole → N-(4-(4-amino-3,3-dimethylpiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:17])[c:6](-[c:8]2[cH:9][nH:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]23)[n:7]1.[NH2:18][c:19]1[c:20]([O:34][CH3:35])[cH:21][c:22]([N:25]2[CH2:26][C:27]([CH3:32])([CH3:33])[CH:28]([NH2:31])[CH2:29][CH2:30]2)[cH:23][cH:24]1>>[c:2]1([NH:18][c:19]2[c:20]([O:34][CH3:35])[cH:21][c:22]([N:25]3[CH2:26][C:27]([CH3:32])([CH3:33])[CH:28]([NH2:31])[CH2:29][CH2:30]3)[cH:23][cH:24]2)[n:3][cH:4][c:5]([Cl:17])[c:6](-[c:8]2[cH:9][nH:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]23)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-3c48494c5b004dfb8f8453415c0d7e15
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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