3-(N-Acetyl-N-methylamino)pyrrolidine → N-methyl-N-(1-((9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)methyl)pyrrolidin-3-yl)acetamide

HRID 1217215Notes

Reaction equation

HRID 1217215 reaction equation
[Br:1][CH2:2][c:3]1[n:4]([CH3:28])[c:5]2[n:6][c:7](-[n:18]3[c:19]([CH3:27])[n:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[n:11]1.[CH3:29][N:30]([C:31]([CH3:32])=[O:33])[CH:34]1[CH2:35][NH:36][CH2:37][CH2:38]1>>[CH2:2]([c:3]1[n:4]([CH3:28])[c:5]2[n:6][c:7](-[n:18]3[c:19]([CH3:27])[n:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[n:11]1)[N:36]1[CH2:35][CH:34]([N:30]([CH3:29])[C:31]([CH3:32])=[O:33])[CH2:38][CH2:37]1

Participants

3

Reactant 2

HCID 130411303-(N-Acetyl-N-methylamino)pyrrolidineHCID 596058124-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine

Product 1

HCID 59605585N-methyl-N-(1-((9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)methyl)pyrrolidin-3-yl)acetamide

Sources & evidence

ORD record
ord-956342bf92c448f2b3e78d642cfbc019
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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