Dichloromethane → N-{[1,6-Diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}-N'-{[6-fluoro-3'-(hydroxymethyl)-3-biphenylyl]methyl}-1,3-benzenedicarboxamide
Reaction equation
[Cl:75][CH2:76][Cl:77].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:16][NH:17][C:18](=[O:19])[c:20]2[cH:21][c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27][cH:28]2)[cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:14][OH:15])[cH:11][cH:12][cH:13]1.[NH2:29][CH2:30][c:31]1[c:32]([NH:44][CH:45]2[CH2:46][CH2:47][O:48][CH2:49][CH2:50]2)[c:33]2[c:34]([n:35][c:36]1[CH2:37][CH3:38])[n:39]([CH2:42][CH3:43])[n:40][cH:41]2.[P-:51]([F:52])([F:53])([F:54])([F:55])([F:56])[F:57].[n:58]1([O:59][C:60]([N:61]([CH3:62])[CH3:63])=[N+:64]([CH3:65])[CH3:66])[c:67]2[cH:68][cH:69][cH:70][cH:71][c:72]2[n:73][n:74]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:16][NH:17][C:18](=[O:19])[c:20]2[cH:21][c:22]([C:23](=[O:24])[NH:29][CH2:30][c:31]3[c:32]([NH:44][CH:45]4[CH2:46][CH2:47][O:48][CH2:49][CH2:50]4)[c:33]4[c:34]([n:35][c:36]3[CH2:37][CH3:38])[n:39]([CH2:42][CH3:43])[n:40][cH:41]4)[cH:26][cH:27][cH:28]2)[cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:14][OH:15])[cH:11][cH:12][cH:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7a3fc6eea6e54409a87ebd4230bf9418
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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