3-Pyridinylboronic acid → 3-(4-Pyridin-3-ylfuran-2-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one

HRID 1217567Notes

Reaction equation

HRID 1217567 reaction equation
[Br:1][c:2]1[cH:3][c:4]([N:7]2[C:8](=[O:19])[O:9][C:10]3([CH2:11][N:12]4[CH2:13][CH2:14][CH:15]3[CH2:16][CH2:17]4)[CH2:18]2)[o:5][cH:6]1.[n:20]1[cH:21][c:22]([B:26]([OH:27])[OH:28])[cH:23][cH:24][cH:25]1>>[c:2]1(-[c:22]2[cH:21][n:20][cH:25][cH:24][cH:23]2)[cH:3][c:4]([N:7]2[C:8](=[O:19])[O:9][C:10]3([CH2:11][N:12]4[CH2:13][CH2:14][CH:15]3[CH2:16][CH2:17]4)[CH2:18]2)[o:5][cH:6]1

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 690553823-(4-Bromofuran-2-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one

Product 1

HCID 690553173-(4-Pyridin-3-ylfuran-2-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one

Sources & evidence

ORD record
ord-c990d9e2577e4b8ab852cfb7151f7ebd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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