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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1217768Generated: November 2, 2026

Acetic Acid → (+/-)-3'-(1-((1-Methyl-4-phenylpiperidin-4-yl)methoxy)ethyl)-5'-(trifluoromethyl)biphenyl-4-carbonitrile

https://huagongshe.com/reaction/1217768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantCyano-borohydrideHCID 498716—
Reactant(+/-)-tert-Butyl 4-((1-(4'-cyano-5-(trifluoromethyl)biphenyl-3-yl)ethoxy)methyl)-4-phenylpiperidine-1-carboxylateHCID 58993681—
Product(+/-)-3'-(1-((1-Methyl-4-phenylpiperidin-4-yl)methoxy)ethyl)-5'-(trifluoromethyl)biphenyl-4-carbonitrileHCID 24785983—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-94ba33f26c324087a7c05d49e358627f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)