Methanol → Tert-butyl 1-(4-amino-2-fluorophenyl)cyclopropane-1-carboxylate
Reaction equation
[CH3:22][OH:23].[F:1][c:2]1[c:3]([C:11]2([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:4][cH:5][c:6]([N+:8]([O-:9])=[O:10])[cH:7]1.[Pd:21]>>[F:1][c:2]1[c:3]([C:11]2([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:4][cH:5][c:6]([NH2:8])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-e79df12a04f34e019fb1f90e1a32f3a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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