(Iodomethyl)cyclopentane → 4-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([OH:27])[c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH2:13][c:14]2[c:15]([F:22])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:23][cH:24][cH:25][cH:26]3)[cH:6][cH:7]1.[I:28][CH2:29][CH:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[Cl:1][c:2]1[cH:3][c:4]([O:27][CH2:29][CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34]2)[c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH2:13][c:14]2[c:15]([F:22])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:23][cH:24][cH:25][cH:26]3)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f405f706824c419bab7ac427a996f56b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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