Water → 3-Bromomethyl-7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-4-oxo-2-phenylthieno[2,3-b]pyridine
Reaction equation
[Br:32][N:33]1[C:34](=[O:35])[CH2:36][CH2:37][C:38]1=[O:39].[C:40]([O:41][CH3:42])(=[O:43])[CH3:44].[F:1][c:2]1[c:3]([CH2:4][n:5]2[c:6]3[c:7]([c:8](=[O:16])[c:9]([C:11]([CH:12]([CH3:13])[CH3:14])=[O:15])[cH:10]2)[c:17]([CH3:26])[c:18](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[s:19]3)[c:27]([F:31])[cH:28][cH:29][cH:30]1.[OH2:45]>>[F:1][c:2]1[c:3]([CH2:4][n:5]2[c:6]3[c:7]([c:8](=[O:16])[c:9]([C:11]([CH:12]([CH3:13])[CH3:14])=[O:15])[cH:10]2)[c:17]([CH2:26][Br:32])[c:18](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[s:19]3)[c:27]([F:31])[cH:28][cH:29][cH:30]1Participants
5
Sources & evidence
- ORD record
- ord-f3fe1855141d417bbd0c2817a0ccb5ea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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