Hexamethylphosphoramide → 2-Aminopyridine-3-carbothioamide

HRID 1218543Notes

Reaction equation

[CH3:11][Si:12]([CH3:13])([CH3:14])[O:15][Si:16]([CH3:17])([CH3:18])[CH3:19].[CH3:34][N:35]([P:36]([N:37]([CH3:38])[CH3:39])([N:40]([CH3:41])[CH3:42])=[O:43])[CH3:44].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[NH2:6])[cH:7][cH:8][cH:9][n:10]1.[P:20]12(=[S:21])[S:22][P:23]3(=[S:33])[S:24][P:25](=[S:31])([S:26][P:27](=[S:30])([S:28]3)[S:29]1)[S:32]2>>[NH2:1][c:2]1[c:3]([C:4]([NH2:6])=[S:21])[cH:7][cH:8][cH:9][n:10]1

Participants

Reactant 4

HCID 12679Hexamethylphosphoramide

HCID 14817Phosphorus sulfide (P2S5)

HCID 24764Hexamethyldisiloxane

HCID 5066232-Aminopyridine-3-carboxamide

Product 1

HCID 226330932-Aminopyridine-3-carbothioamide

Sources & evidence

ORD record: ord-5ec5cacb87a241bdb5cde66d53d2bc58
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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