N,N-Dimethylacrylamide → 4-amino-N-{1-[3-(dimethylamino)-3-oxopropyl]piperidin-3-yl}-3-(3-methoxy-4-{[(1-methyl-1H-indol-2-yl)carbonyl]amino}phenyl)thieno[3,2-c]pyridine-7-carboxamide
Reaction equation
[CH3:41][N:42]([C:43]([CH:44]=[CH2:45])=[O:46])[CH3:47].[NH2:1][c:2]1[n:3][cH:4][c:5]([C:32](=[O:33])[NH:34][CH:35]2[CH2:36][NH:37][CH2:38][CH2:39][CH2:40]2)[c:6]2[c:7]1[c:8](-[c:11]1[cH:12][c:13]([O:30][CH3:31])[c:14]([NH:17][C:18](=[O:19])[c:20]3[n:21]([CH3:29])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[cH:28]3)[cH:15][cH:16]1)[cH:9][s:10]2>>[NH2:1][c:2]1[n:3][cH:4][c:5]([C:32](=[O:33])[NH:34][CH:35]2[CH2:36][N:37]([CH2:45][CH2:44][C:43]([N:42]([CH3:41])[CH3:47])=[O:46])[CH2:38][CH2:39][CH2:40]2)[c:6]2[c:7]1[c:8](-[c:11]1[cH:12][c:13]([O:30][CH3:31])[c:14]([NH:17][C:18](=[O:19])[c:20]3[n:21]([CH3:29])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[cH:28]3)[cH:15][cH:16]1)[cH:9][s:10]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-124261b427e64ceb899bf62fa9c5a8a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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