2-Aminopyridine → 6-Bromo-8-cyclopentyl-2-(pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([S:10]([CH3:11])=[O:12])[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15].[NH2:21][c:22]1[n:23][cH:24][cH:25][cH:26][cH:27]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([NH:21][c:22]3[n:23][cH:24][cH:25][cH:26][cH:27]3)[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15]Participants
3
Sources & evidence
- ORD record
- ord-cc9b9157ec2940fc9a419c9e9cc86d8d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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