Methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate → Methyl 4-{3-[4-(2-biphenyl-4-ylethyl)phenyl]propoxy}-3-({[3-(methoxycarbonyl)-cyclohexyl]amino}carbonyl)benzoate

HRID 1218807Notes

Reaction equation

HRID 1218807 reaction equation
[I:25][CH2:26][CH2:27][CH2:28][c:29]1[cH:30][cH:31][c:32]([CH2:35][CH2:36][c:37]2[cH:38][cH:39][c:40](-[c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[cH:41][cH:42]2)[cH:33][cH:34]1.[OH:1][c:2]1[c:3]([C:12](=[O:13])[NH:14][CH:15]2[CH2:16][CH:17]([C:21](=[O:22])[O:23][CH3:24])[CH2:18][CH2:19][CH2:20]2)[cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1>>[O:1]([c:2]1[c:3]([C:12](=[O:13])[NH:14][CH:15]2[CH2:16][CH:17]([C:21](=[O:22])[O:23][CH3:24])[CH2:18][CH2:19][CH2:20]2)[cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1)[CH2:26][CH2:27][CH2:28][c:29]1[cH:30][cH:31][c:32]([CH2:35][CH2:36][c:37]2[cH:38][cH:39][c:40](-[c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[cH:41][cH:42]2)[cH:33][cH:34]1

Participants

3

Reactant 2

HCID 57589182Methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoateHCID 690813904-{2-[4-(3-Iodopropyl)phenyl]ethyl}biphenyl

Product 1

HCID 57589234Methyl 4-{3-[4-(2-biphenyl-4-ylethyl)phenyl]propoxy}-3-({[3-(methoxycarbonyl)-cyclohexyl]amino}carbonyl)benzoate

Sources & evidence

ORD record
ord-c9cd7eec1ce74f0a9f3af1223f21bcc6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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