Dichloromethane → Benzyl 2-(4-(chlorocarbonyl)-3-fluorophenyl)pyrrolidine-1-carboxylate

HRID 1218836Notes

Reaction equation

HRID 1218836 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([c:16]2[cH:17][c:18]([F:25])[c:19]([C:20](=[O:21])[OH:22])[cH:23][cH:24]2)[CH2:13][CH2:14][CH2:15]1.[Cl:30][CH2:31][Cl:32].[S:26]([Cl:27])([Cl:28])=[O:29]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([c:16]2[cH:17][c:18]([F:25])[c:19]([C:20](=[O:21])[Cl:28])[cH:23][cH:24]2)[CH2:13][CH2:14][CH2:15]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 666213044-(1-(Benzyloxycarbonyl)pyrrolidin-2-yl)-2-fluorobenzoic acid

Product 1

HCID 86633086Benzyl 2-(4-(chlorocarbonyl)-3-fluorophenyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-13885d24ff404df99cc79901682c54e1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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