3-Iodomethyl-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester → 3-[4-(5-Cyano-pyrimidin-2-yl)-phenoxymethyl]-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester
Reaction equation
[CH2:16]([CH3:17])[O:18][C:19](=[O:20])[C:21]1([CH2:36][I:37])[CH2:22][N:23]([C:26]([c:27]2[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]2)=[O:35])[CH2:24][CH2:25]1.[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([C:14]#[N:15])[cH:12][n:13]2)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([C:14]#[N:15])[cH:12][n:13]2)[cH:6][cH:7]1)[CH2:36][C:21]1([C:19]([O:18][CH2:16][CH3:17])=[O:20])[CH2:22][N:23]([C:26]([c:27]2[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]2)=[O:35])[CH2:24][CH2:25]1Participants
3
Sources & evidence
- ORD record
- ord-118b5b0cf94842a39dc9aa494994b5be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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