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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1219432Generated: October 25, 2026

Dimethylformamide → 5-fluoro-N-(trans-4-hydroxy-cyclohexyl)-2-(4-methylsulfanyl-3-methyl-phenoxy)-nicotinamide

https://huagongshe.com/reaction/1219432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant3-Methyl-4-(methylthio)phenolHCID 18391—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
Reactant2-Chloro-5-fluoro-N-(trans-4-hydroxycyclohexyl)nicotinamideHCID 21877165—
Product5-fluoro-N-(trans-4-hydroxy-cyclohexyl)-2-(4-methylsulfanyl-3-methyl-phenoxy)-nicotinamideHCID 21877181—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-7717ded111064da5b5bc4d26e11213a7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)