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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12196Generated: October 25, 2026

2-Methylnicotinic acid → N-(6-chloro-7-cyclopropylmethoxy-9H-beta-carbolin-8-yl)-2-methyl-nicotinamide

https://huagongshe.com/reaction/12196

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylnicotinic acidHCID 643373—
Reactant6-chloro-7-cyclopropylmethoxy-9H-beta-carbolin-8-ylamineHCID 67165212—
ProductN-(6-chloro-7-cyclopropylmethoxy-9H-beta-carbolin-8-yl)-2-methyl-nicotinamideHCID 1128122640%

Reaction Steps

The desired compound was prepared according to Method A from 6-chloro-7-cyclopropylmethoxy-9H-β-carbolin-8-ylamine and 2-methylnicotinic acid in a 40-60% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727985B2
Source datasetuspto-grants-2010_06
ORD IDord-970f2d8f6a31410c9eb7931d5d8ac635
Source noteuspto-grants-2010_06