1,2-Dichlorobenzene → 2-isopropyl-6-{6-[(4-methoxybenzyl)amino]-3-phenyl-2-pyrazinyl}-3(2H)-pyridazinone

HRID 121976Notes

Reaction equation

HRID 121976 reaction equation
[CH:1]([n:2]1[c:3](=[O:4])[cH:5][cH:6][c:7](-[c:8]2[n:9][c:10]([C:11]([OH:12])=[O:13])[c:14]([NH:15][CH2:16][c:17]3[cH:18][cH:19][c:20]([O:21][CH3:22])[cH:23][cH:24]3)[n:25][c:26]2-[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[n:33]1)([CH3:34])[CH3:35].[CH:36]([CH3:37])([CH3:38])[n:39]1[n:40][c:41](-[c:46]2[n:47][c:48]([NH:61][CH2:62][c:63]3[cH:64][cH:65][c:66]([O:69][CH3:70])[cH:67][cH:68]3)[c:49]([C:58]([OH:59])=[O:60])[n:50][c:51]2-[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[cH:42][cH:43][c:44]1=[O:45].[Cl:71][c:72]1[cH:73][cH:74][cH:75][cH:76][c:77]1[Cl:78]>>[CH:36]([CH3:37])([CH3:38])[n:39]1[n:40][c:41](-[c:46]2[n:47][c:48]([NH:61][CH2:62][c:63]3[cH:64][cH:65][c:66]([O:69][CH3:70])[cH:67][cH:68]3)[cH:49][n:50][c:51]2-[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[cH:42][cH:43][c:44]1=[O:45]

Participants

4

Reactant 3

HCID 72391,2-DichlorobenzeneHCID 693315096-(1-Isopropyl-6-oxo-1,6-dihydro-3-pyridazinyl)-3-[(4-methoxybenzyl)amino]-5-phenyl-2-pyrazinecarboxylic acidHCID 693319635-(1-Isopropyl-6-oxo-1,6-dihydro-3-pyridazinyl)-3-[(4-methoxybenzyl)amino]-6-phenyl-2-pyrazinecarboxylic acid

Product 1

HCID 693319672-isopropyl-6-{6-[(4-methoxybenzyl)amino]-3-phenyl-2-pyrazinyl}-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-e501d0659c15496f81061667e2588ade
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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