Acetone → 3-iodo-2-methoxy-5-methyl-6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepine
Reaction equation
[CH3:27][I:28].[CH3:50][OH:51].[CH3:52][C:53](=[O:54])[CH3:55].[I:1][c:2]1[c:3]([OH:4])[n:5][c:6]2[c:19]([cH:20]1)[CH:17]([CH3:18])[CH2:16][N:9]([C:10](=[O:11])[C:12]([F:13])([F:14])[F:15])[CH2:8][CH2:7]2.[I:29][c:30]1[cH:31][c:32]2[c:33]([n:46][c:47]1[O:48][CH3:49])[CH2:34][CH2:35][N:36]([C:40](=[O:41])[C:42]([F:43])([F:44])[F:45])[CH2:37][CH:38]2[CH3:39].[K+:21].[K+:22].[O-:23][C:24]([O-:25])=[O:26]>>[I:29][c:30]1[cH:31][c:32]2[c:33]([n:46][c:47]1[O:48][CH3:49])[CH2:34][CH2:35][NH:36][CH2:37][CH:38]2[CH3:39]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0a025203a7fe4ccbad1569f9bdb6ad38
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…