Ethyl bromoacetate → ethyl 1-[(5,6-dichloro-9a-methyl-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]cyclopentane-1-carboxylate

HRID 1220461Notes

Reaction equation

HRID 1220461 reaction equation
[Br:20][CH2:21][C:22]([O:23][CH2:24][CH3:25])=[O:26].[Br:45][C:46]1([C:51](=[O:52])[O:53][CH2:54][CH3:55])[CH2:47][CH2:48][CH2:49][CH2:50]1.[Cl:1][c:2]1[c:3]([Cl:4])[c:5]([OH:6])[cH:7][c:8]2[c:9]1[C:10]1=[CH:19][C:17](=[O:18])[CH2:16][CH2:15][C:11]1([CH2:12][CH3:13])[CH2:14]2.[Cl:27][c:28]1[c:29]2[c:37]([cH:38][c:39]([OH:42])[c:40]1[Cl:41])[CH2:36][C:35]1([CH3:43])[C:30]2=[CH:31][C:32](=[O:44])[CH2:33][CH2:34]1>>[Cl:27][c:28]1[c:29]2[c:37]([cH:38][c:39]([O:42][C:46]3([C:51](=[O:52])[O:53][CH2:54][CH3:55])[CH2:47][CH2:48][CH2:49][CH2:50]3)[c:40]1[Cl:41])[CH2:36][C:35]1([CH3:43])[C:30]2=[CH:31][C:32](=[O:44])[CH2:33][CH2:34]1

Participants

5

Reactant 4

HCID 7748Ethyl bromoacetateHCID 128069355,6-dichloro-9a-ethyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-oneHCID 136133345,6-dichloro-7-hydroxy-9a-methyl-1,2,9,9a-tetrahydro-3H-fluoren-3-oneHCID 15301050Ethyl 1-bromocyclopentane-1-carboxylate

Product 1

HCID 20520807ethyl 1-[(5,6-dichloro-9a-methyl-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]cyclopentane-1-carboxylate

Sources & evidence

ORD record
ord-580e6601ed004c26966c3d2824e0054e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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