Bromide ion → 1-Chloro-4-(4-fluoro-benzyl)-6,7-dihydro-5H-cyclopenta[d]pyridazine

HRID 1220484Notes

Reaction equation

HRID 1220484 reaction equation
[Br-:12].[Cl:1][c:2]1[n:3][n:4][c:5]([Cl:11])[c:6]2[c:7]1[CH2:8][CH2:9][CH2:10]2.[F:13][c:14]1[cH:15][cH:16][c:17]([CH2:18][Zn+:19])[cH:20][cH:21]1>>[c:2]1([CH2:18][c:17]2[cH:16][cH:15][c:14]([F:13])[cH:21][cH:20]2)[n:3][n:4][c:5]([Cl:11])[c:6]2[c:7]1[CH2:8][CH2:9][CH2:10]2

Participants

4

Reactant 3

HCID 259Bromide ionHCID 154019081,4-dichloro-5H,6H,7H-cyclopenta[d]pyridazineHCID 178505762HCID 178505762, compound

Product 1

HCID 591914921-Chloro-4-(4-fluoro-benzyl)-6,7-dihydro-5H-cyclopenta[d]pyridazine

Sources & evidence

ORD record
ord-c329ce4082974356adefd7dd916e4cb6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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