HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 122050Generated: October 25, 2026
Hydrochloric Acid → 5-Bromo-N-((1SR,2RS)-2-hydroxy-cyclohexyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
https://huagongshe.com/reaction/122050
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 2-Aminocyclohexanol | HCID 23286 | — |
| Reactant | Tetrafluoroborate | HCID 26255 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-benzotriazol-1-yl-tetramethyluronium | HCID 130500 | — |
| Reactant | 5-Bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid | HCID 58192592 | — |
| Product | 5-Bromo-N-((1SR,2RS)-2-hydroxy-cyclohexyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinamide | HCID 58192591 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
|---|
| ORD ID | ord-35d2cb99173c46c1b5e735a47d01f2d1 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
|---|
