4-Fluorobenzoyl chloride → 2-(4-Fluorophenyl)-6-hydroxybenzothiazole

HRID 1220837Notes

Reaction equation

HRID 1220837 reaction equation
[F:11][c:12]1[cH:13][cH:14][c:15]([C:16]([Cl:17])=[O:18])[cH:19][cH:20]1.[F:21][c:22]1[cH:23][cH:24][c:25](-[c:28]2[s:29][c:30]3[c:31]([n:32]2)[cH:33][cH:34][c:35]([O:37][CH3:38])[cH:36]3)[cH:26][cH:27]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH3:7])[cH:8][c:9]1[SH:10]>>[F:21][c:22]1[cH:23][cH:24][c:25](-[c:28]2[s:29][c:30]3[c:31]([n:32]2)[cH:33][cH:34][c:35]([OH:37])[cH:36]3)[cH:26][cH:27]1

Participants

4

Reactant 3

HCID 678794-Fluorobenzoyl chlorideHCID 2355092-Amino-5-methoxybenzene-1-thiolHCID 121799872-(4-Fluorophenyl)-6-methoxy-1,3-benzothiazole

Product 1

HCID 167341662-(4-Fluorophenyl)-6-hydroxybenzothiazole

Sources & evidence

ORD record
ord-6562a08351ce4e3ba3c2a2f73c664c67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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