3-(4-Methylpiperazin-1-yl)aniline → [8-(2-Methoxy-5-trifloromethylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine

HRID 1220949Notes

Reaction equation

HRID 1220949 reaction equation
[CH3:23][N:24]1[CH2:25][CH2:26][N:27]([c:30]2[cH:31][c:32]([NH2:36])[cH:33][cH:34][cH:35]2)[CH2:28][CH2:29]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6](-[c:10]3[c:11]([O:20][CH3:21])[cH:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]3)[cH:7][cH:8][cH:9]2)[n:22]1>>[c:2]1([NH:36][c:32]2[cH:31][c:30]([N:27]3[CH2:26][CH2:25][N:24]([CH3:23])[CH2:29][CH2:28]3)[cH:35][cH:34][cH:33]2)[n:3][n:4]2[c:5]([c:6](-[c:10]3[c:11]([O:20][CH3:21])[cH:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]3)[cH:7][cH:8][cH:9]2)[n:22]1

Participants

3

Reactant 2

HCID 115646133-(4-Methylpiperazin-1-yl)anilineHCID 674789492-Chloro-8-(2-methoxy-5-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridine

Product 1

HCID 59612404[8-(2-Methoxy-5-trifloromethylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine

Sources & evidence

ORD record
ord-e7dde0b2aae34a9e9c0409e85a04f0bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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