Piperazin-2-one → 4-{3-[5-(2-Fluoro-phenyl)-thiophen-2-yl]-acryloyl}-piperazin-2-one
Reaction equation
[F:1][c:2]1[c:3](-[c:8]2[cH:9][cH:10][c:11]([CH:13]=[CH:14][C:15](=[O:16])[OH:17])[s:12]2)[cH:4][cH:5][cH:6][cH:7]1.[NH:18]1[C:19](=[O:24])[CH2:20][NH:21][CH2:22][CH2:23]1>>[F:1][c:2]1[c:3](-[c:8]2[cH:9][cH:10][c:11]([CH:13]=[CH:14][C:15](=[O:17])[N:21]3[CH2:20][C:19](=[O:24])[NH:18][CH2:23][CH2:22]3)[s:12]2)[cH:4][cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-1e93834cb90b442380edfaca0fbe30b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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