Potassium Cation → N-(3-{1-(5-(4-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 1221005Notes

Reaction equation

HRID 1221005 reaction equation
[CH3:21][CH:22]([C:23](=[O:24])[NH:25][c:26]1[cH:27][c:28]([CH:32]2[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2)[cH:29][cH:30][cH:31]1)[CH3:38].[Cl:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12](=[O:13])[c:14]1[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]1.[K+:1].[K+:2].[O-:3][C:4]([O-:5])=[O:6]>>[CH2:8]([CH2:9][CH2:10][CH2:11][C:12](=[O:13])[c:14]1[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]1)[N:35]1[CH2:34][CH2:33][CH:32]([c:28]2[cH:27][c:26]([NH:25][C:23]([CH:22]([CH3:21])[CH3:38])=[O:24])[cH:31][cH:30][cH:29]2)[CH2:37][CH2:36]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 126497945-Chloro-1-(4-fluorophenyl)-1-oxopentaneHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049378N-(3-{1-(5-(4-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Sources & evidence

ORD record
ord-774f685112a14021b0fc15d877b4a4cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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