Dichloromethane → 2-(4-Acetamidophenyl)-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolin-6-ol

HRID 1221014Notes

Reaction equation

HRID 1221014 reaction equation
[B:31]([Br:32])([Br:33])[Br:34].[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[cH:6][cH:7][c:8]([N:11]2[CH:12]([CH2:23][c:24]3[cH:25][cH:26][c:27]([OH:30])[cH:28][cH:29]3)[c:13]3[cH:14][cH:15][c:16]([O:21][CH3:22])[cH:17][c:18]3[CH2:19][CH2:20]2)[cH:9][cH:10]1.[Cl:35][CH2:36][Cl:37]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[cH:6][cH:7][c:8]([N:11]2[CH:12]([CH2:23][c:24]3[cH:25][cH:26][c:27]([OH:30])[cH:28][cH:29]3)[c:13]3[cH:14][cH:15][c:16]([OH:21])[cH:17][c:18]3[CH2:19][CH2:20]2)[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 234407862-(4-Acetamidophenyl)-1-(4-hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 99522432-(4-Acetamidophenyl)-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolin-6-ol

Sources & evidence

ORD record
ord-cf9640854c2a4286b75e990883f553c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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