6,8-Difluoro-2-tetralone → 3-{4-[2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoylamino]-imidazol-1-yl}-3-methyl-butyric acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][C:5]([CH3:6])([CH3:7])[n:8]1[cH:9][n:10][c:11]([NH:13][C:14]([CH:15]([CH2:16][CH2:17][CH3:18])[NH2:19])=[O:20])[cH:12]1)=[O:21].[F:22][c:23]1[cH:24][c:25]2[c:30]([c:31]([F:33])[cH:32]1)[CH2:29][C:28](=[O:34])[CH2:27][CH2:26]2>>[CH3:1][O:2][C:3]([CH2:4][C:5]([CH3:6])([CH3:7])[n:8]1[cH:9][n:10][c:11]([NH:13][C:14]([CH:15]([CH2:16][CH2:17][CH3:18])[NH:19][CH:28]2[CH2:27][CH2:26][c:25]3[cH:24][c:23]([F:22])[cH:32][c:31]([F:33])[c:30]3[CH2:29]2)=[O:20])[cH:12]1)=[O:21]Participants
3
Sources & evidence
- ORD record
- ord-3714d9af65b24270a87ea9eba22604e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…