5-Ethynylpyridin-2-amine → 5-[6-(4-Chloro-phenyl)-8-cyclopropyl-imidazo[1,2-a]pyridin-3-ylethynyl]-pyridin-2-ylamine

HRID 1221123Notes

Reaction equation

HRID 1221123 reaction equation
[C:21](#[CH:22])[c:23]1[cH:24][cH:25][c:26]([NH2:29])[n:27][cH:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH:18]3[CH2:19][CH2:20]3)[c:11]3[n:12]([cH:13]2)[c:14]([I:17])[cH:15][n:16]3)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH:18]3[CH2:19][CH2:20]3)[c:11]3[n:12]([cH:13]2)[c:14]([C:22]#[C:21][c:23]2[cH:24][cH:25][c:26]([NH2:29])[n:27][cH:28]2)[cH:15][n:16]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 219548275-Ethynylpyridin-2-amineHCID 670009596-(4-Chloro-phenyl)-8-cyclopropyl-3-iodo-imidazo[1,2-a]pyridine

Product 1

HCID 670008695-[6-(4-Chloro-phenyl)-8-cyclopropyl-imidazo[1,2-a]pyridin-3-ylethynyl]-pyridin-2-ylamine

Sources & evidence

ORD record
ord-cc6a8568a0204c3f8b1d52b43868fdaf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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