Toluene → 4-(6-(Bromomethyl)-2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)morpholine

HRID 1221252Notes

Reaction equation

HRID 1221252 reaction equation
[CH3:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[c:8]([CH3:13])[c:9]([CH2:11][OH:12])[s:10]2.[P:20]([Br:21])([Br:22])[Br:23]>>[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[c:8]([CH3:13])[c:9]([CH2:11][Br:21])[s:10]2

Participants

4

Reactant 3

HCID 1140TolueneHCID 24614Phosphorus tribromideHCID 78358255(2-Chloro-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol

Product 1

HCID 783582564-(6-(Bromomethyl)-2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)morpholine

Sources & evidence

ORD record
ord-6e44564f0b6c44a8a53203ec2945816d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…