HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1221285Generated: November 2, 2026
Citric Acid → 3-[3-[tert-butyl(dimethyl)silyl]oxyazetidin-1-yl]-2-[1-(2-chlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-N-(5-fluoro-2-pyridinyl)propanamide
https://huagongshe.com/reaction/1221285
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Hydride | HCID 166653 | — |
| Reactant | 4-Chloro-1-(2-chlorophenyl)-1H-pyrazolo[3,4-D]pyrimidine | HCID 11265570 | — |
| Reactant | 3-[3-[tert-butyl(dimethyl)silyl]oxyazetidin-1-yl]-N-(5-fluoro-2-pyridinyl)-2-hydroxypropanamide | HCID 66813213 | — |
| Product | 3-[3-[tert-butyl(dimethyl)silyl]oxyazetidin-1-yl]-2-[1-(2-chlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-N-(5-fluoro-2-pyridinyl)propanamide | HCID 76550511 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
|---|
| ORD ID | ord-2e66a06e490b4489b26caf3a770c23e0 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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