{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → (1-[4-(4-oxo-2-phenyl-6-trifluoromethoxy-4H-chromen-3-yl)-phenyl]-cyclobutyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](-[c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[o:20][c:21]4[cH:22][cH:23][c:24]([F:29])[cH:25][c:26]4[c:27]3=[O:28])[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36].[I:37][c:38]1[c:39](=[O:40])[c:41]2[c:42]([cH:43][cH:44][c:45]([O:49][C:50]([F:51])([F:52])[F:53])[cH:46]2)[o:47][c:48]1-[c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](-[c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[o:20][c:21]4[cH:22][cH:23][c:24]([O:49][C:50]([F:51])([F:52])[F:53])[cH:25][c:26]4[c:27]3=[O:28])[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-26588212f4354b5d8602d8901159170d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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