Aniline → 4-(5-amino-2-fluorophenyl)-6,6-difluoro-4,7a-bis(fluoromethyl)-5,7-dihydro-4aH-cyclopenta[e][1,3]oxazin-2-amine
Reaction equation
[F:8][C:9]1([F:33])[CH2:10][C:11]2([CH2:31][F:32])[CH:12]([C:13]([CH2:18][F:19])([c:20]3[c:21]([F:29])[cH:22][cH:23][c:24]([N+:26]([O-:27])=[O:28])[cH:25]3)[N:14]=[C:15]([NH2:17])[O:16]2)[CH2:30]1.[NH2:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[F:8][C:9]1([F:33])[CH2:10][C:11]2([CH2:31][F:32])[CH:12]([C:13]([CH2:18][F:19])([c:20]3[c:21]([F:29])[cH:22][cH:23][c:24]([NH2:26])[cH:25]3)[N:14]=[C:15]([NH2:17])[O:16]2)[CH2:30]1Participants
3
Sources & evidence
- ORD record
- ord-9c112b1500ae40f3aad26c0e238d2c45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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