ethyl [3-(3-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate → ethyl [3-(hydroxymethyl)-3-(3-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate

HRID 1221568Notes

Reaction equation

HRID 1221568 reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:6][c:7]2[c:8]1[CH:9]([c:10]1[c:11]([OH:12])[cH:13][c:14]3[c:19]([cH:20]1)[O:18][CH2:17][O:15]3)[C:5](=[O:16])[N:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].[OH:27][c:28]1[c:29]([CH:38]2[C:39](=[O:53])[N:40]([CH2:47][C:48](=[O:49])[O:50][CH2:51][CH3:52])[c:41]3[cH:42][cH:43][cH:44][cH:45][c:46]32)[cH:30][c:31]2[c:36]([cH:37]1)[CH2:35][CH2:34][CH2:33][CH2:32]2>>[CH2:5]([OH:16])[C:38]1([c:29]2[c:28]([OH:27])[cH:37][c:36]3[c:31]([cH:30]2)[CH2:32][CH2:33][CH2:34][CH2:35]3)[C:39](=[O:53])[N:40]([CH2:47][C:48](=[O:49])[O:50][CH2:51][CH3:52])[c:41]2[cH:42][cH:43][cH:44][cH:45][c:46]21

Participants

3

Reactant 2

HCID 58872466ethyl [3-(3-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetateHCID 588725004-bromo-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 58872462ethyl [3-(hydroxymethyl)-3-(3-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate

Sources & evidence

ORD record
ord-04d300fb01754e44b99ca2b184331044
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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