5-Bromo-2-(trifluoromethyl)pyrimidine → 5-(4-{[1-(1-Methylethyl)-4-piperidinyl]methyl}-1-piperidinyl)-2-(trifluoromethyl)pyrimidine
Reaction equation
[Br:17][c:18]1[cH:19][n:20][c:21]([C:24]([F:25])([F:26])[F:27])[n:22][cH:23]1.[CH3:1][CH:2]([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[CH2:8][CH2:9]1>>[CH3:1][CH:2]([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][CH:11]2[CH2:12][CH2:13][N:14]([c:18]3[cH:19][n:20][c:21]([C:24]([F:25])([F:26])[F:27])[n:22][cH:23]3)[CH2:15][CH2:16]2)[CH2:8][CH2:9]1Participants
3
Sources & evidence
- ORD record
- ord-ef22d054908348e7be22149adc9ef9ee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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