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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1221765Generated: November 2, 2026

Dichloromethane → 1'-(2,2,2-trifluoroacetyl)spiro[indene-1,4'-piperidin]-3(2H)-one

https://huagongshe.com/reaction/1221765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
ReactantTrifluoroacetic anhydrideHCID 9845—
Reactant4-(Dimethylamino)pyridineHCID 14284—
ReactantTert-butyl 3-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylateHCID 18673579—
Product1'-(2,2,2-trifluoroacetyl)spiro[indene-1,4'-piperidin]-3(2H)-oneHCID 19366992—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-d8d11aef3b314972a13056296e821f64
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)