Ethyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylate → Ethyl 1-((4-(6-benzylbenzofuran-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([F:18])[cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH:9]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[CH2:10]2)[cH:16][cH:17]1.[CH2:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[c:26]1[cH:27][c:28]2[c:29]([cH:30][c:31]([B:33]([OH:34])[OH:35])[o:32]2)[cH:36][cH:37]1>>[c:2]1(-[c:31]2[cH:30][c:29]3[c:28]([cH:27][c:26]([CH2:19][c:20]4[cH:21][cH:22][cH:23][cH:24][cH:25]4)[cH:37][cH:36]3)[o:32]2)[c:3]([F:18])[cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH:9]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[CH2:10]2)[cH:16][cH:17]1Participants
3
Sources & evidence
- ORD record
- ord-ed37b3fb70bd4acd9a7729fda74707b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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