Methanol → Tert-butyl 2-(2,2-dimethylpropoxy)-5-(hydroxymethyl)morpholine-4-carboxylate

HRID 122187Notes

Reaction equation

HRID 122187 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:23][CH2:24][C:25]([CH3:26])([CH3:27])[CH3:28])[O:11][CH2:12][CH:13]1[CH2:14][O:15][CH2:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1.[CH3:31][OH:32].[H:29][H:30].[OH-:33].[OH-:35].[Pd+2:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:23][CH2:24][C:25]([CH3:26])([CH3:27])[CH3:28])[O:11][CH2:12][CH:13]1[CH2:14][OH:15]

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 77514798Tert-butyl 2-(2,2-dimethylpropoxy)-5-(phenylmethoxymethyl)morpholine-4-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 77515064Tert-butyl 2-(2,2-dimethylpropoxy)-5-(hydroxymethyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-2e9c74683f9b4bf8963555cd8a0dfccb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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