Sodium ion → Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

HRID 1222001Notes

Reaction equation

HRID 1222001 reaction equation
[C:28]([OH:29])([CH3:30])([CH3:31])[CH3:32].[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][c:4]([Cl:8])[cH:5][n:6][cH:7]1.[Na+:22].[Na+:23].[O-:24][C:25](=[O:26])[O-:27]>>[c:2]1([N:19]2[CH2:18][CH2:17][N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:21][CH2:20]2)[n:3][c:4]([Cl:8])[cH:5][n:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6386tert-ButanolHCID 19660Carbonate IonHCID 785042,6-DichloropyrazineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 18186946Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-dab00eb063884bffae66e83d0be43634
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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