Potassium Cation → 3-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-[5-(3-hydroxypropyl)-3-thienyl]-1H-indole-7-carboxamide

HRID 1222483Notes

Reaction equation

HRID 1222483 reaction equation
[Br:36][c:37]1[cH:38][c:39]([CH2:42][CH2:43][CH2:44][OH:45])[s:40][cH:41]1.[CH2:47]1[O:48][CH2:49][CH2:50][O:51][CH2:52]1.[K+:30].[K+:31].[O-:32][C:33]([O-:34])=[O:35].[O:1]=[S:2]1(=[O:29])[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[c:12]([C:26](=[O:27])[NH2:28])[cH:13][c:14]([B:17]4[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]4)[cH:15][c:16]23)[CH2:6][CH2:7]1.[OH2:46]>>[O:1]=[S:2]1(=[O:29])[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[c:12]([C:26](=[O:27])[NH2:28])[cH:13][c:14](-[c:37]4[cH:38][c:39]([CH2:42][CH2:43][CH2:44][OH:45])[s:40][cH:41]4)[cH:15][c:16]23)[CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 593327113-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-7-carboxamideHCID 626030043-(4-Bromothiophen-2-yl)propan-1-ol

Product 1

HCID 593325783-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-[5-(3-hydroxypropyl)-3-thienyl]-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-00213a0e8bf04cc49133ce2a5fc41218
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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