Dimethyl Sulfoxide → N4-(5-tert-butylisoxazol-3-yl)-N2-(3,4,5-trimethoxy-phenyl)-pyrimidine-2,4-diamine

HRID 1222637Notes

Reaction equation

HRID 1222637 reaction equation
[CH3:18][O:19][c:20]1[cH:21][c:22]([NH2:23])[cH:24][c:25]([O:29][CH3:30])[c:26]1[O:27][CH3:28].[CH3:31][S:32]([CH3:33])=[O:34].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][c:9]2[n:10][o:11][c:12]([C:14]([CH3:15])([CH3:16])[CH3:17])[cH:13]2)[n:7]1>>[c:2]1([NH:23][c:22]2[cH:21][c:20]([O:19][CH3:18])[c:26]([O:27][CH3:28])[c:25]([O:29][CH3:30])[cH:24]2)[n:3][cH:4][cH:5][c:6]([NH:8][c:9]2[n:10][o:11][c:12]([C:14]([CH3:15])([CH3:16])[CH3:17])[cH:13]2)[n:7]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 322853,4,5-TrimethoxyanilineHCID 21936452(2-Chloro-pyrimidin-4-yl)-(5-tert-butyl-isoxazol-3-yl)-amine

Product 1

HCID 10172969N4-(5-tert-butylisoxazol-3-yl)-N2-(3,4,5-trimethoxy-phenyl)-pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-efbec33dc1aa471ba85490e67c14d32d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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