1-(Bromomethyl)-4-(trifluoromethyl)benzene → Ethyl 2-(3-((5-chlorobenzo[b]thiophen-3-yl)methyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate

HRID 1222805Notes

Reaction equation

HRID 1222805 reaction equation
[Br:13][CH2:14][c:15]1[c:16]2[c:17]([s:18][cH:19]1)[cH:20][cH:21][c:22]([Cl:24])[cH:23]2.[CH3:25][c:26]1[n:27][c:28]([N:36]2[C:37](=[O:41])[NH:38][CH2:39][CH2:40]2)[s:29][c:30]1[C:31](=[O:32])[O:33][CH2:34][CH3:35].[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][Br:10])[cH:11][cH:12]1>>[CH2:14]([c:15]1[c:16]2[c:17]([s:18][cH:19]1)[cH:20][cH:21][c:22]([Cl:24])[cH:23]2)[N:38]1[C:37](=[O:41])[N:36]([c:28]2[n:27][c:26]([CH3:25])[c:30]([C:31](=[O:32])[O:33][CH2:34][CH3:35])[s:29]2)[CH2:40][CH2:39]1

Participants

4

Reactant 3

HCID 1230621-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 27798573-(Bromomethyl)-5-chloro-1-benzothiopheneHCID 57919776Ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate

Product 1

HCID 58031618Ethyl 2-(3-((5-chlorobenzo[b]thiophen-3-yl)methyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate

Sources & evidence

ORD record
ord-14029bfe9335453abf323770bcf0f798
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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