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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1222855Generated: October 25, 2026

N-(3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide → N-(3-fluoro-4-(2-(3-(4-(hydroxymethyl)piperidin-1-yl)-3-methylbut-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

https://huagongshe.com/reaction/1222855

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHCID 67347909—
Reactant(1-(2-Methylbut-3-yn-2-yl)piperidin-4-yl)methanolHCID 86614650—
ProductN-(3-fluoro-4-(2-(3-(4-(hydroxymethyl)piperidin-1-yl)-3-methylbut-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHCID 67345514—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-bcb304c8759d425a9b1625071d32ca33
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)