Diethyl Ether → 2-{4-[(4-Fluorophenyl)methyl]piperidin-1-yl}-N-(2-hydroxy-1,3-benzoxazol-6-yl)-2-oxoacetamide

HRID 1222861Notes

Reaction equation

HRID 1222861 reaction equation
[CH2:31]([O:32][CH2:33][CH3:34])[CH3:35].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[CH2:8][CH2:9][N:10]([C:13]([C:14](=[O:15])[OH:16])=[O:17])[CH2:11][CH2:12]2)[cH:18][cH:19]1.[NH2:20][c:21]1[cH:22][c:23]2[c:24]([nH:25][c:26](=[O:28])[o:27]2)[cH:29][cH:30]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[CH2:8][CH2:9][N:10]([C:13]([C:14](=[O:16])[NH:20][c:21]3[cH:22][c:23]4[c:24]([nH:25][c:26](=[O:28])[o:27]4)[cH:29][cH:30]3)=[O:17])[CH2:11][CH2:12]2)[cH:18][cH:19]1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 8269896-amino-1,3-benzoxazol-2(3H)-oneHCID 51342220[4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acid

Product 1

HCID 102008132-{4-[(4-Fluorophenyl)methyl]piperidin-1-yl}-N-(2-hydroxy-1,3-benzoxazol-6-yl)-2-oxoacetamide

Sources & evidence

ORD record
ord-8c53399debef4d4fb49dbfa4348d2c60
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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