Thiopheneethanamine → N-[(4-fluorophenyl)methyl]-4-hydroxy-N-methyl-5-oxo-1-[2-(2-thienyl)ethyl]-2H-pyrrole-3-carboxamide

HRID 1222903Notes

Reaction equation

HRID 1222903 reaction equation
[CH3:1][O:2][C:3](=[O:4])[C:5]([OH:6])=[CH:7][C:8](=[O:9])[N:10]([CH2:11][c:12]1[cH:13][cH:14][c:15]([F:16])[cH:17][cH:18]1)[CH3:19].[F:28][c:29]1[cH:30][cH:31][c:32]([CH2:33][N:34]([C:35](=[O:36])[C:37]2=[C:41]([OH:42])[C:40](=[O:43])[N:39]([CH3:44])[CH2:38]2)[CH3:45])[cH:46][cH:47]1.[s:20]1[c:21]([CH2:25][CH2:26][NH2:27])[cH:22][cH:23][cH:24]1>>[s:20]1[c:21]([CH2:25][CH2:26][N:27]2[CH2:38][C:37]([C:35]([N:34]([CH2:33][c:32]3[cH:31][cH:30][c:29]([F:28])[cH:47][cH:46]3)[CH3:45])=[O:36])=[C:41]([OH:42])[C:40]2=[O:43])[cH:22][cH:23][cH:24]1

Participants

4

Reactant 3

HCID 116521ThiopheneethanamineHCID 54698182N-[(4-fluorophenyl)methyl]-4-hydroxy-N,1-dimethyl-5-oxo-2H-pyrrole-3-carboxamideHCID 696556793-[(4-Fluoro-benzyl)-methyl-carbamoyl]-2-hydroxy-acrylic acid methyl ester

Product 1

HCID 54698185N-[(4-fluorophenyl)methyl]-4-hydroxy-N-methyl-5-oxo-1-[2-(2-thienyl)ethyl]-2H-pyrrole-3-carboxamide

Sources & evidence

ORD record
ord-0a7368fff3b94e5abc6605ce84a6337f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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