Acetic Acid → tert-butyl N-[3-[4-[(3-chlorophenyl)methylamino]piperidin-1-yl]butyl]carbamate

HRID 1222916Notes

Reaction equation

HRID 1222916 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH:10]([CH3:11])[N:12]1[CH2:13][CH2:14][C:15](=[O:18])[CH2:16][CH2:17]1)=[O:19].[CH3:29][C:30](=[O:31])[OH:32].[Cl:20][c:21]1[cH:22][c:23]([CH2:24][NH2:25])[cH:26][cH:27][cH:28]1.[Cl:33][CH2:34][Cl:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH:10]([CH3:11])[N:12]1[CH2:13][CH2:14][CH:15]([NH:25][CH2:24][c:23]2[cH:22][c:21]([Cl:20])[cH:28][cH:27][cH:26]2)[CH2:16][CH2:17]1)=[O:19]

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 6344DichloromethaneHCID 77802Benzenemethanamine, 3-chloro-HCID 68775260[3-(4-Oxo-piperidin-1-yl)-butyl]-carbamic acid tert-butyl ester

Product 1

HCID 68774081tert-butyl N-[3-[4-[(3-chlorophenyl)methylamino]piperidin-1-yl]butyl]carbamate

Sources & evidence

ORD record
ord-4e4461c0df714c3f811ff76df496f10b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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