HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(1-oxobutan-2-yl)carbamate → 4-(2-Amino-butyl)-6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(1-oxobutan-2-yl)carbamate | HCID 11286906 | — |
| Reactant | 5-(6-chloro-9H-beta-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholine-4-carboxylic acid tert-butyl ester | HCID 67164497 | — |
| Product | 4-(2-Amino-butyl)-6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide | HCID 67164417 | — |
Reaction Steps
Method C was followed, using 5-(6-chloro-9H-β-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholine-4-carboxylic acid tert-butyl ester and the appropriate aldehyde, (1-formyl-propyl)-carbamic acid tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07727985B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-ff9c6f32cd5a4c24819f000ea55e2c8b |
| Source note | uspto-grants-2010_06 |