2-Fluoro-6-methylpyridine-3-boronic acid → 4-amino-N-cyclopropyl-8-(2-fluoro-6-methylpyridin-3-yl)cinnoline-3-carboxamide
Reaction equation
[F:19][c:20]1[n:21][c:22]([CH3:29])[cH:23][cH:24][c:25]1[B:26]([OH:27])[OH:28].[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH:16]2[CH2:17][CH2:18]2)[n:4][n:5][c:6]2[c:7]([Br:12])[cH:8][cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH:16]2[CH2:17][CH2:18]2)[n:4][n:5][c:6]2[c:7](-[c:25]3[c:20]([F:19])[n:21][c:22]([CH3:29])[cH:23][cH:24]3)[cH:8][cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-5fadc303741349ada32ebad8805207ac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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