Piperidine, 4-(1,1-dimethylethyl)- → 4-[4-(tert-Butyl)piperidin-1-yl]-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[CH:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1.[CH3:1][S:2][c:3]1[n:4][c:5]([CH2:12][c:13]2[cH:14][s:15][cH:16][cH:17]2)[nH:6][c:7](=[O:11])[c:8]1[C:9]#[N:10]>>[c:3]1([N:25]2[CH2:24][CH2:23][CH:22]([C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:27][CH2:26]2)[n:4][c:5]([CH2:12][c:13]2[cH:14][s:15][cH:16][cH:17]2)[nH:6][c:7](=[O:11])[c:8]1[C:9]#[N:10]Participants
3
Sources & evidence
- ORD record
- ord-891b8ac36be644b6a7b0f6bfefc2baf1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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